Aims

This ICL will focus on exciting discoveries in the area of stem cell therapy, skeletal dysplasia, Legg-Calve-Perthes disease, and clubfoot. Four distinguished speakers with their expertise in these areas will provide clinically relevant presentations followed by a panel discussion on the impact of basic research on clinical practice. This ICL will cater to pediatric orthopaedic surgeons.

Objectives

• To highlight the regenerative and immunomodulatory properties of mesenchymal stem cells and their clinical applications in the treatment of various orthopaedic conditions, such as osteonecrosis, cartilage, and physeal damage.
• To provide an overview of molecular diagnosis of skeletal dysplasia using next-generation sequencing, and to present strategy and experience of discovering the causative gene for specific skeletal dysplasia.
• To discuss the latest discoveries on the pathophysiology of Legg-Calve-Perthes disease and potential biological therapies that are on the horizon.
• To present the genetics and its association with the epidemiology of clubfoot. The role of environmental factors, especially heavy metals, and genetic biomarkers will be discussed.

Program:

Hall	Time	Topic	Watch Video
HALL C (IFPOS HALL)	14:00 - 14:20	Stem Cell Research and Application in Pediatric Orthopaedics (includes a short question period of 2-3 minutes): Dr. James Hui	View
HALL C (IFPOS HALL)	14:20 - 14:40	Discovery of Causative Gene / Mutation and Molecular Diagnosis of Skeletal Dysplasia : Dr. Tae-Joon Cho	View
HALL C (IFPOS HALL)	14:40 - 15:00	Advances in Perthes Disease Research and Discoveries: Dr. Harry Kim
HALL C (IFPOS HALL)	15:00 - 15:20	Genetics & Basic Research in Clubfoot: Dr. Ajai Singh	View
HALL C (IFPOS HALL)	15:20 - 15:30	Panel Discussion: Impact of Research on Clinical Practice: Dr. Ajai Singh, Dr. Tae-Joon Cho, Dr. James Hui, Dr. Harry Kim

Team POSICON 2019 thanks Dr. Ashok Shyam / Orthotv for Video editing and uploading.